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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN9
All Species:
12.73
Human Site:
S496
Identified Species:
25.45
UniProt:
P43378
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43378
NP_002824.1
593
68020
S496
N
Q
Q
S
L
A
V
S
N
M
G
A
R
S
K
Chimpanzee
Pan troglodytes
XP_001144390
596
67599
S499
N
Q
Q
S
L
A
V
S
N
M
G
A
R
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854411
607
69728
S510
N
Q
Q
R
L
A
V
S
S
M
G
V
R
A
K
Cat
Felis silvestris
Mouse
Mus musculus
O35239
593
67952
G496
N
Q
Q
S
M
A
V
G
N
L
G
A
R
S
K
Rat
Rattus norvegicus
Q641Z2
593
67944
G496
S
Q
Q
S
M
A
V
G
S
L
G
A
R
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505361
613
70033
S516
H
Q
Q
R
V
A
V
S
A
L
G
P
R
S
R
Chicken
Gallus gallus
XP_413696
584
66275
A487
V
K
Q
Q
Q
R
V
A
V
S
A
L
G
P
R
Frog
Xenopus laevis
NP_001081203
694
79518
Q594
Q
H
Q
A
V
A
V
Q
N
L
G
M
E
W
T
Zebra Danio
Brachydanio rerio
XP_001923429
571
65239
K474
I
D
F
L
G
A
V
K
H
Q
Q
Q
W
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727356
797
85738
Q696
E
K
Q
A
Q
L
V
Q
G
L
G
D
T
W
A
Honey Bee
Apis mellifera
XP_394701
660
73346
A558
Q
Q
Q
T
K
L
L
A
S
R
G
D
T
W
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200442
281
32148
T185
K
E
M
G
D
E
W
T
G
H
P
G
G
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
N.A.
92
N.A.
97.3
97.1
N.A.
75.8
74
44.3
67.7
N.A.
35.6
43.4
N.A.
25.8
Protein Similarity:
100
94.6
N.A.
94.4
N.A.
98.6
98.9
N.A.
87.4
84.4
61
81.6
N.A.
49.1
60.6
N.A.
34.2
P-Site Identity:
100
100
N.A.
73.3
N.A.
80
66.6
N.A.
53.3
13.3
33.3
13.3
N.A.
20
20
N.A.
0
P-Site Similarity:
100
100
N.A.
86.6
N.A.
93.3
93.3
N.A.
80
33.3
53.3
26.6
N.A.
40
46.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
67
0
17
9
0
9
34
0
17
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
0
0
0
0
0
0
17
0
0
0
% D
% Glu:
9
9
0
0
0
9
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
9
0
0
17
17
0
75
9
17
0
0
% G
% His:
9
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
17
0
0
9
0
0
9
0
0
0
0
0
0
42
% K
% Leu:
0
0
0
9
25
17
9
0
0
42
0
9
0
0
0
% L
% Met:
0
0
9
0
17
0
0
0
0
25
0
9
0
0
0
% M
% Asn:
34
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
9
0
17
9
% P
% Gln:
17
59
84
9
17
0
0
17
0
9
9
9
0
0
0
% Q
% Arg:
0
0
0
17
0
9
0
0
0
9
0
0
50
0
17
% R
% Ser:
9
0
0
34
0
0
0
34
25
9
0
0
0
42
0
% S
% Thr:
0
0
0
9
0
0
0
9
0
0
0
0
17
0
9
% T
% Val:
9
0
0
0
17
0
84
0
9
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
9
25
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _